The Sinclair Method: Science-Based Freedom from Alcohol Dependency
Key Takeaways:
The Sinclair Method (TSM) uses medication and neuroscience to reduce alcohol cravings
It boasts a 78% long-term success rate, reshaping alcohol recovery worldwide
TSM enables people to regain control without the need for total abstinence
Combining TSM with coaching and education increases effectiveness significantly
Rethink Drink offers a free screening call and introductory resources for support
What Is the Sinclair Method?
The Sinclair Method (TSM) is an evidence-based treatment for alcohol use disorder (AUD) that is transforming lives across the globe. Unlike traditional abstinence-only models, TSM enables individuals to gradually unlearn alcohol dependency using a medication called Naltrexone.
At its core, TSM is rooted in neuroscience and the concept of pharmacological extinction — a strategy that aims to break the brain’s association between alcohol and pleasure. This method doesn’t demand immediate sobriety. Instead, it offers a gentler path to recovery by retraining the brain to lose interest in alcohol naturally.
TSM is compassionate, data-driven, and ideal for those who haven’t found success in conventional recovery approaches.
How the Sinclair Method Works
Here’s a simplified overview of the step-by-step process:
Take Naltrexone: Before drinking, users take a tablet of Naltrexone (typically 50mg) at least one hour in advance.
Drink as Usual: Alcohol consumption continues, but the reward system in the brain is muted by the medication.
Block Endorphins: Naltrexone blocks the feel-good chemicals usually released during drinking, reducing the pleasurable reinforcement.
Rewire the Brain: Over time, as drinking no longer provides the same satisfaction, the brain starts to detach alcohol from reward.
Cravings Decrease: Users often notice a steady decline in cravings, frequency, and the amount of alcohol they consume.
Control Returns: For many, alcohol becomes something they can take or leave — or they choose to stop entirely.
This process is supported by research showing a 78% success rate for those who follow the protocol consistently. It’s a realistic and empowering approach for those who want to regain control, without facing a “one-size-fits-all” treatment path.
A Different Approach to Recovery
What makes TSM so powerful is its flexibility and respect for individual choice. Rather than framing alcohol as the enemy or demanding total abstinence from day one, TSM treats the habitual behaviour — not the person — as the root of the problem.
Thousands have already turned to this method as an alternative to willpower-based sobriety. It’s particularly helpful for:
Individuals seeking a non-shaming, science-based path to recovery
People who’ve struggled with relapse or find AA-style methods unrelatable
Those who want to reduce harm gradually and regain autonomy
At Rethink Drink, we specialise in helping people integrate TSM into their lives effectively. We offer coaching, support, and education to guide every step of the journey.
Get Support with Rethink Drink
To maximise the effectiveness of TSM, having structure and guidance is crucial. Many people who use TSM on their own plateau or misuse the protocol without realising it. That’s where we come in.
Learn the fundamentals in our free mini course, designed to explain the science and process of TSM.
If you're ready to explore whether this is right for you, book a free screening call and chat with someone who truly understands the method.
Our community and coaching can help personalise your path to success, with empathy and lived experience at its core.
Why the Sinclair Method Is Changing the Future of Alcohol Treatment
For decades, alcohol treatment revolved around abstinence and the notion that relapse equals failure. But the world is changing — and so is the science.
The Sinclair Method challenges outdated assumptions and puts evidence and empowerment at the heart of recovery. With long-term success rates that far surpass most other treatments, it’s no wonder more and more people are rethinking how they drink.
Whether you’re looking to cut down or take control once and for all, TSM offers a path forward that works with your brain, not against it.