FAQs About The Sinclair Method: What You Really Need to Know
Key Takeaways
The Sinclair Method (TSM) uses naltrexone to reduce the pleasurable effects of alcohol.
It allows individuals to drink while gradually reducing consumption.
Success depends on consistently taking naltrexone before drinking.
TSM is backed by scientific research and real-world success stories.
Free tools, courses, and coaching can support you on the journey.
What is The Sinclair Method?
The Sinclair Method is a treatment for Alcohol Use Disorder (AUD) that involves taking the medication naltrexone one hour before drinking. Naltrexone blocks endorphins released by alcohol, reducing the brain’s reinforcement of drinking behaviour. Over time, this leads to a natural decrease in alcohol consumption—a process known as pharmacological extinction.
Unlike traditional methods that require immediate abstinence, TSM allows for gradual change while still drinking. Many find this more sustainable and realistic.
How effective is The Sinclair Method?
TSM boasts a success rate of around 78%, according to multiple studies and clinical observations. This figure is significantly higher than many abstinence-based programmes, particularly because it aligns with real-world drinking behaviours.
The effectiveness is enhanced when users receive support such as coaching, follow structured steps, and consistently use naltrexone.
Do I have to stop drinking immediately?
No. One of the core appeals of The Sinclair Method is that you do not have to stop drinking right away. In fact, continued drinking is essential for the medication to work properly. Over time, as the brain's reward loop weakens, the urge to drink decreases naturally.
This approach reduces the guilt, shame, and pressure often associated with quitting “cold turkey”.
What is naltrexone and is it safe?
Naltrexone is an opioid antagonist, which means it blocks the opioid receptors in the brain. When you drink alcohol after taking naltrexone, it blocks the endorphins that create feelings of euphoria or pleasure.
Naltrexone is:
Non-addictive
Not mood-altering
Generally well tolerated by most people
Common side effects may include mild nausea, fatigue, or dizziness during the first few days of use.
For a more detailed overview, visit our Sinclair Method FAQ guide.
How long does The Sinclair Method take to work?
This varies from person to person, but typically:
Noticeable changes begin in 1–3 months
Significant reductions occur within 3–6 months
Full pharmacological extinction may take up to a year
Factors that influence this include consistency, frequency of drinking, and whether you're using support tools or coaching.
What happens if I drink without taking naltrexone?
If you drink without naltrexone, you:
Reinforce the reward loop in the brain
Risk undoing previous progress
May experience stronger cravings over time
While one mistake won’t ruin everything, repeated lapses can slow or reverse your results. Need help staying consistent? Try our free TSM mini-course to stay on track.
Can I take naltrexone every day?
You only take naltrexone:
When you plan to drink
Around 1–2 hours before alcohol consumption
If you’re not drinking, you do not take the medication. This targeted method prevents unnecessary interference with your body’s natural endorphin system.
Is coaching necessary for success?
While not mandatory, coaching is highly recommended for those looking to maximise their results. With a coach, you can:
Stay motivated and accountable
Troubleshoot obstacles or setbacks
Tailor your approach to your lifestyle
Feel supported through each stage of the process
Book a free screening call if you’re curious about working with a Sinclair Method coach.
Can TSM work for binge drinking or weekend drinking?
Absolutely. The Sinclair Method is effective for:
Weekend binge drinkers
Social or situational drinkers
High-functioning individuals who don’t drink daily
As long as naltrexone is taken before drinking, the process of pharmacological extinction still occurs—regardless of drinking frequency.
What if I relapse after success?
Relapses happen, and TSM is designed to be forgiving. If you stop taking the medication and return to old patterns:
Simply resume naltrexone before drinking
Rebuild consistency to re-establish extinction
Seek additional support if needed
Remember, this is a long-term approach. You’re not starting from scratch—you’re continuing a journey.
Quick Recap: Sinclair Method at a Glance
✅ TSM uses naltrexone to reduce cravings
✅ You can continue drinking while on the method
✅ Naltrexone must be taken before every drinking session
✅ It's non-addictive and generally well tolerated
✅ TSM is effective for both daily and occasional drinkers
✅ Coaching improves success rates
✅ Lapses are manageable with proper support
Ready to take the first step? Book your free screening call or enrol in our free TSM mini-course to learn more and start your journey with confidence.